On the infusion of a therapeutic agent into a solid tumor modeled as a poroelastic medium.

An Asymptotic Formulation for the Infusion of a Therapeutic Agent into a Solid Tumor Modeled as a Poroelastic Medium

Plane Strain Deformation of a Poroelastic Half-Space Lying Over Another Poroelastic Half-Space

The plane strain deformation of an isotropic, homogeneous, poroelastic medium caused by an inclined line-load is studied using the Biot linearized theory for fluid saturated porous materials. The analytical expressions for the displacements and stresses in the medium are obtained by applying suitable boundary conditions. The solutions are obtained analytically for the limiting case of undrained...

An Algorithm for Modeling and Interpretation of Seismoelectric Data

Generally speaking, seismoelectric modeling is a prospecting method based on seismic and electromagnetic waves, in which waves generated by a seismic source at the boundary of the two environments generate a relative fluid-solid motion formed as a result of antagonism between the elastic properties of the environment with the saturated fluid. This research has as its objective, a study of the e...

Aptamer-based Targeted Delivery of miRNA let-7d to Gastric Cancer Cells as a Novel Anti-Tumor Therapeutic Agent

miRNAs as one of the potential therapeutic agents have been recently considered for cancer treatment. AS1411 (aptNCL) is a DNA aptamer specifically binding to nucleolin protein on the cancer cell surface with antiproliferative effect. The aim of the study was to develop a conjugate consisted of aptNCL (as targeted delivery of therapeutic agent) and miRNA let-7d (as a tumor suppressor) using two...

Study of Torsional Vibrations of Composite Poroelastic Spherical Shell-Biot’s Extension Theory

Torsional vibrations of composite poroelastic dissipative spherical shell are investigated in the framework of Biot’s extension theory.Here composite poroelastic spherical shell consists of two spherical shells, one is placed on other, and both are made of different poroelastic materials. Consideration of the stress-free boundaries of outer surface and the perfect bonding between two shells lea...